Scientists have succeeded in killing proteins they could not remove with a new method called 'kiss of death.' This has been a big turning point in cancer treatment. The developments, which we have compiled the details of from the Huffington Post, has excited the medical world.
For a long time, researchers have known about the vital role that proteins play in spreading cancerous tumors around the human body.
Now the team at the University of Dundee has found a way to neutralize these stubborn proteins, which had previously been deemed untouchable by drugs.
The process works by introducing small molecules to target these bad proteins, that then bind to them, neutralize them, and start a chain of events that degrades them and breaks them down in the body.
However, in the past, the major stumbling block has been finding the molecules that would work to bind and at the same time hamper functionality. As proteins can often fool regulators within the cell and can be difficult to pin down.
So instead of using these small molecules to locate and disable the protein, the new study, is working on a way to attract the neutralizing proteins, which then bind to the bad neighbor and act against it.
"And not just a little peck, but a real `Gone With The Wind’ embrace. We call this a ‘kiss of death,’ as it is the key to ensure the degradation of the bad protein.”